Kisspeptin-10 10mg lyophilized research peptide vial by Method Peptides

KissPeptin-10

$65.00
Dose: 10mg
≥99% purity
Third-party tested
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Kisspeptin-10

Kisspeptin-10 (KP-10) is the biologically active C-terminal decapeptide of human kisspeptin. It is studied for its interaction with the kisspeptin receptor, KISS1R/GPR54, and its role in neuroendocrine signaling, gonadotropin-releasing hormone pathways, and reproductive-axis research.

In laboratory settings, Kisspeptin-10 is commonly evaluated in models involving hypothalamic signaling, GnRH neuronal activity, luteinizing hormone and follicle-stimulating hormone pathways, reproductive development, and communication within the hypothalamic-pituitary-gonadal axis.

The Method

10mg vial. Lyophilized peptide. Lot-specific quality documentation. Sterile vial integrity.

Key Research Areas

  • KISS1R/GPR54 receptor research involving kisspeptin-mediated receptor activation
  • GnRH signaling models involving hypothalamic neuroendocrine communication
  • Gonadotropin pathway research involving luteinizing hormone and follicle-stimulating hormone signaling
  • Reproductive-axis research involving hypothalamic-pituitary-gonadal pathway regulation
  • Puberty and reproductive-development models involving KISS1 and KISS1R signaling
  • Neuroendocrine feedback studies involving reproductive hormones and central signaling pathways

Mechanism of Interest

Kisspeptin-10 binds to KISS1R, formerly known as GPR54, a G-protein-coupled receptor involved in reproductive neuroendocrine signaling. Receptor activation is associated with Gq-mediated phospholipase C signaling, phosphatidylinositol pathway activity, intracellular calcium mobilization, and downstream cellular communication.

Within neuroendocrine research models, KISS1R activation is studied for its relationship to GnRH neuronal signaling. GnRH pathway activity can subsequently influence pituitary luteinizing hormone and follicle-stimulating hormone signaling, making Kisspeptin-10 an important research tool for studying communication throughout the reproductive axis.

Product Size: 10mg vial
Compound Class: Synthetic neuroendocrine decapeptide / KISS1R receptor agonist
Sequence: Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH₂
Molecular Formula: C₆₃H₈₃N₁₇O₁₄
Molecular Weight: 1302.4 g/mol
CAS Number: 374675-21-5
Synonyms: KP-10, Kisspeptin-10 Human, Human Metastin 45–54
Composition: Kisspeptin-10 lyophilized peptide
Storage: Store lyophilized material in a cool, dry, light-protected environment according to lot-specific instructions. Refrigeration is recommended after reconstitution. Minimize repeated freeze-thaw cycles.

Why Researchers Study Kisspeptin-10

Kisspeptin-10 has gained substantial research interest because KISS1 and KISS1R signaling represents a major regulatory pathway connecting the hypothalamus with reproductive hormone signaling. The peptide provides a defined research model for examining receptor activation, GnRH-related communication, and downstream gonadotropin pathways.

Researchers also study Kisspeptin-10 in models involving reproductive development, puberty-related signaling, hormonal feedback, hypothalamic activity, and the broader relationship between metabolic and reproductive neuroendocrine systems.

Research Use Only:

This product is intended strictly for laboratory and research purposes. Not for human consumption, medical use, diagnostic use, or therapeutic use.

Storage Information
Form: Lyophilized powder (white to off-white) Dry powder (unreconstituted): Stable at –4 °F (–20 °C) for up to 24 months when sealed, dry, and protected from light Reconstituted solution: Store at 36–46 °F (2–8 °C) and use within 30 days Avoid repeated freeze–thaw cycles to maintain peptide integrity
CAS / Compound Information
Sequence: Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH₂ Molecular Formula: C₆₃H₈₃N₁₇O₁₄ Molecular Weight: 1302.44 g/mol PubChem CID: 25240297 CAS Number: 374675-21-5 Synonyms: Kisspeptin-10, KP-10, Metastin (45–54), KISS1 (112–121)-amide

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