PE 22-28

$480.00
Size: 10mg (10 Vials)
≥99% purity
Third-party tested
Ships from the USA
Secure research packaging
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Restricted to laboratory and analytical research

Products in this catalog are supplied as research materials only. They are not drugs, foods, cosmetics, supplements, or medical devices and are not intended to diagnose, treat, cure, or prevent disease.

Compound overview

Product specifications, research context, and handling information.

PE 22-28

PE 22-28 is a seven-amino-acid peptide derived from spadin and studied in potassium-channel research.

Preclinical experiments examine TREK-1 channel activity, neuronal excitability, and responses to shortened spadin analogs. This listing is supplied as a kit of 10 vials, with per-vial amounts shown in Product Details.

Key Research Areas

  • TREK-1 electrophysiology
  • Neuronal-excitability models
  • Spadin-analog comparisons
  • Peptide structure–activity studies

Mechanism of Interest

PE 22-28 has been reported to inhibit TREK-1, a two-pore-domain potassium channel, in electrophysiological assays. Channel activity and downstream cellular effects require separate measurement.

Product Details

Format: Kit of 10 vials
Available Options: 10 mg per vial × 10 vials = 100 mg per kit
Compound Class: Spadin-derived heptapeptide
Compound: PE 22-28
Storage: Follow the product label and lot-specific storage instructions. Prepared-sample storage depends on formulation and validated laboratory stability conditions.

Potassium Channels and Neural Activity

TREK-1 channels contribute to neuronal electrical activity. PE 22-28 research uses channel measurements to examine how inhibition changes excitability and how shorter spadin-derived peptides interact with this target.

Research Use Only:

This product is intended strictly for laboratory and research purposes. Not for human consumption, medical use, diagnostic use, or therapeutic use.