Method Peptides · Research compound

PE 22-28

$480.00
Size: 10mg (10 Vials)
≥99% purity
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Research reference

Compound overview

Product specifications, research context, and handling information.

PE 22-28

PE 22-28 is a seven-amino-acid peptide derived from spadin and studied in potassium-channel research.

Preclinical experiments examine TREK-1 channel activity, neuronal excitability, and responses to shortened spadin analogs. This listing is supplied as a kit of 10 vials, with per-vial amounts shown in Product Details.

Key Research Areas

  • TREK-1 electrophysiology
  • Neuronal-excitability models
  • Spadin-analog comparisons
  • Peptide structure–activity studies

Mechanism of Interest

PE 22-28 has been reported to inhibit TREK-1, a two-pore-domain potassium channel, in electrophysiological assays. Channel activity and downstream cellular effects require separate measurement.

Product Details

Format: Kit of 10 vials
Available Options: 10 mg per vial × 10 vials = 100 mg per kit
Compound Class: Spadin-derived heptapeptide
Compound: PE 22-28
Storage: Follow the product label and lot-specific storage instructions. Prepared-sample storage depends on formulation and validated laboratory stability conditions.

Potassium Channels and Neural Activity

TREK-1 channels contribute to neuronal electrical activity. PE 22-28 research uses channel measurements to examine how inhibition changes excitability and how shorter spadin-derived peptides interact with this target.

Research Use Only:

This product is intended strictly for laboratory and research purposes. Not for human consumption, medical use, diagnostic use, or therapeutic use.