Method Peptides · Research compound
PE 22-28
$15 flat rate on orders under $200.
Allow 7–10 business days before shipment.
Method Peptides · Research compound
$15 flat rate on orders under $200.
Allow 7–10 business days before shipment.
Research reference
Product specifications, research context, and handling information.
PE 22-28 is a seven-amino-acid peptide derived from spadin and studied in potassium-channel research.
Preclinical experiments examine TREK-1 channel activity, neuronal excitability, and responses to shortened spadin analogs. This listing is supplied as a kit of 10 vials, with per-vial amounts shown in Product Details.
PE 22-28 has been reported to inhibit TREK-1, a two-pore-domain potassium channel, in electrophysiological assays. Channel activity and downstream cellular effects require separate measurement.
TREK-1 channels contribute to neuronal electrical activity. PE 22-28 research uses channel measurements to examine how inhibition changes excitability and how shorter spadin-derived peptides interact with this target.
This product is intended strictly for laboratory and research purposes. Not for human consumption, medical use, diagnostic use, or therapeutic use.