{"product_id":"topical-finasteride-60-ml","title":"Finasteride (Topical)","description":"\u003cdiv style=\"max-width:820px;margin:0 auto;padding:20px 0;color:#122026;line-height:1.6\"\u003e\n\u003ch2 style=\"color:#154ba3\"\u003eTopical Finasteride — 60 mL\u003c\/h2\u003e\n\u003cp\u003eFinasteride is a synthetic 4-azasteroid supplied here as a liquid research solution in an ethanol and USP propylene glycol vehicle.\u003c\/p\u003e\n\u003cdiv style=\"background:#f7faff;border-left:4px solid #154ba3;border-radius:12px;padding:16px;margin:18px 0\"\u003e\n\u003ch3 style=\"color:#154ba3\"\u003eKey Research Areas\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eType 2 5-alpha-reductase inhibition\u003c\/li\u003e\n\u003cli\u003eTestosterone conversion to dihydrotestosterone (DHT)\u003c\/li\u003e\n\u003cli\u003eAndrogen signaling in follicular models\u003c\/li\u003e\n\u003cli\u003eSolution and vehicle comparisons\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003ch3 style=\"color:#154ba3\"\u003eMechanism of Interest\u003c\/h3\u003e\n\u003cp\u003eFinasteride inhibits type 2 5-alpha-reductase, the enzyme that converts testosterone to DHT. Its mechanism acts at the level of DHT synthesis. \u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC9297965\/\"\u003eFinasteride pharmacology reference\u003c\/a\u003e\u003c\/p\u003e\n\u003ch3 style=\"color:#154ba3\"\u003eProduct Details\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eFormat:\u003c\/strong\u003e Liquid solution, 60 mL bottle\u003cbr\u003e\u003cstrong\u003eCompound:\u003c\/strong\u003e Finasteride\u003cbr\u003e\u003cstrong\u003eCompound class:\u003c\/strong\u003e Synthetic 4-azasteroid, type 2 5-alpha-reductase inhibitor\u003c\/p\u003e\n\u003ch4 style=\"color:#e8edf5\"\u003e0.1% w\/v\u003c\/h4\u003e\n\u003cp\u003e\u003cstrong\u003eFinasteride:\u003c\/strong\u003e 1 mg\/mL (60 mg per bottle)\u003c\/p\u003e\n\u003ch4 style=\"color:#e8edf5\"\u003e0.3% w\/v\u003c\/h4\u003e\n\u003cp\u003e\u003cstrong\u003eFinasteride:\u003c\/strong\u003e 3 mg\/mL (180 mg per bottle)\u003c\/p\u003e\n\u003ch4 style=\"color:#e8edf5\"\u003eVehicle and volume for both strengths\u003c\/h4\u003e\n\u003cp\u003e\u003cstrong\u003eEthanol:\u003c\/strong\u003e 40 mL (66.67% v\/v)\u003cbr\u003e\u003cstrong\u003eUSP propylene glycol:\u003c\/strong\u003e 20 mL (33.33% v\/v)\u003cbr\u003e\u003cstrong\u003eTarget final volume:\u003c\/strong\u003e 60 mL\u003c\/p\u003e\n\u003ch3 style=\"color:#154ba3\"\u003ePublished Research and Formulation Limits\u003c\/h3\u003e\n\u003cp\u003ePiraccini et al. evaluated a specific 0.25% w\/w finasteride spray in a 24-week randomized Phase III trial in men with androgenetic alopecia. The trial measured target-area hair count and systemic exposure. \u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC9297965\/\"\u003ePhase III trial\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eCaserini et al. evaluated changes in scalp and serum DHT at different applied amounts of a 0.25% topical solution. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26636418\/\"\u003eScalp and serum DHT study\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eBoth studies used specific formulations and delivery conditions. Their results do not establish safety, efficacy, or absorption for the 0.1% or 0.3% w\/v ethanol and propylene glycol solutions listed here.\u003c\/p\u003e\n\u003cdiv style=\"background:#154ba3;color:#fff;border-radius:12px;padding:16px;margin-top:22px\"\u003e\n\u003cstrong\u003eResearch Use Only\u003c\/strong\u003e\u003cp\u003eFor laboratory research only. Not for human consumption, medical, diagnostic, or therapeutic use.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"Method Peptides","offers":[{"title":"0.1% w\/v","offer_id":50760826060938,"sku":null,"price":50.0,"currency_code":"USD","in_stock":true},{"title":"0.3% w\/v","offer_id":50760826093706,"sku":null,"price":80.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0611\/5531\/1754\/files\/1mg-MatteBlackFinasterideDropperBottle.png?v=1794282159","url":"https:\/\/methodpeptides.com\/products\/topical-finasteride-60-ml","provider":"Method Peptides","version":"1.0","type":"link"}