{"product_id":"kisspeptin-10","title":"KissPeptin-10","description":"\u003cdiv style=\"max-width: 820px; margin: 0 auto; padding: 20px 0; font: 16px\/1.6 -apple-system,BlinkMacSystemFont,'Segoe UI',Roboto,Arial,Helvetica,sans-serif; color: #122026;\"\u003e\n\n  \u003c!-- Title --\u003e\n  \u003ch2 style=\"margin: 0 0 6px; font-size: 24px; color: #154ba3;\"\u003e\n    \u003cstrong\u003eKisspeptin-10\u003c\/strong\u003e\n  \u003c\/h2\u003e\n\n  \u003c!-- Intro --\u003e\n  \u003cp style=\"margin: 8px 0 14px;\"\u003e\n    \u003cstrong\u003eKisspeptin-10 (KP-10)\u003c\/strong\u003e is the biologically active C-terminal decapeptide of human kisspeptin. It is studied for its interaction with the kisspeptin receptor, \u003cstrong\u003eKISS1R\/GPR54\u003c\/strong\u003e, and its role in neuroendocrine signaling, gonadotropin-releasing hormone pathways, and reproductive-axis research.\n  \u003c\/p\u003e\n\n  \u003cp style=\"margin: 8px 0 18px;\"\u003e\n    In laboratory settings, Kisspeptin-10 is commonly evaluated in models involving hypothalamic signaling, GnRH neuronal activity, luteinizing hormone and follicle-stimulating hormone pathways, reproductive development, and communication within the hypothalamic-pituitary-gonadal axis.\n  \u003c\/p\u003e\n\n  \u003c!-- The Method --\u003e\n  \u003cdiv style=\"border: 1px solid #e6edf2; border-radius: 10px; padding: 14px 16px; background: #fff; margin: 18px 0;\"\u003e\n    \u003cdiv style=\"font-weight: bold; color: #154ba3; margin-bottom: 6px;\"\u003e\n      The Method\n    \u003c\/div\u003e\n    \u003cp style=\"margin: 0;\"\u003e\n      10mg vial. Lyophilized peptide. Lot-specific quality documentation. Sterile vial integrity.\n    \u003c\/p\u003e\n  \u003c\/div\u003e\n\n  \u003c!-- Key Research Areas --\u003e\n  \u003cdiv style=\"background: #f7faff; border: 1px solid rgba(21,75,163,0.16); border-left: 4px solid #154ba3; border-radius: 12px; padding: 16px; margin: 18px 0;\"\u003e\n    \u003ch3 style=\"margin: 0 0 10px; font-size: 18px; color: #154ba3;\"\u003e\n      Key Research Areas\n    \u003c\/h3\u003e\n\n    \u003cul style=\"margin: 0; padding-left: 20px;\"\u003e\n      \u003cli\u003e\n        \u003cstrong\u003eKISS1R\/GPR54 receptor research\u003c\/strong\u003e involving kisspeptin-mediated receptor activation\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003cstrong\u003eGnRH signaling models\u003c\/strong\u003e involving hypothalamic neuroendocrine communication\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003cstrong\u003eGonadotropin pathway research\u003c\/strong\u003e involving luteinizing hormone and follicle-stimulating hormone signaling\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003cstrong\u003eReproductive-axis research\u003c\/strong\u003e involving hypothalamic-pituitary-gonadal pathway regulation\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003cstrong\u003ePuberty and reproductive-development models\u003c\/strong\u003e involving KISS1 and KISS1R signaling\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003cstrong\u003eNeuroendocrine feedback studies\u003c\/strong\u003e involving reproductive hormones and central signaling pathways\n      \u003c\/li\u003e\n    \u003c\/ul\u003e\n  \u003c\/div\u003e\n\n  \u003c!-- Mechanism --\u003e\n  \u003ch3 style=\"margin: 20px 0 8px; font-size: 19px; color: #154ba3;\"\u003e\n    Mechanism of Interest\n  \u003c\/h3\u003e\n\n  \u003cp style=\"margin: 8px 0 14px;\"\u003e\n    Kisspeptin-10 binds to \u003cstrong\u003eKISS1R\u003c\/strong\u003e, formerly known as GPR54, a G-protein-coupled receptor involved in reproductive neuroendocrine signaling. Receptor activation is associated with Gq-mediated phospholipase C signaling, phosphatidylinositol pathway activity, intracellular calcium mobilization, and downstream cellular communication.\n  \u003c\/p\u003e\n\n  \u003cp style=\"margin: 8px 0 18px;\"\u003e\n    Within neuroendocrine research models, KISS1R activation is studied for its relationship to GnRH neuronal signaling. GnRH pathway activity can subsequently influence pituitary luteinizing hormone and follicle-stimulating hormone signaling, making Kisspeptin-10 an important research tool for studying communication throughout the reproductive axis.\n  \u003c\/p\u003e\n\n  \u003c!-- Product Details --\u003e\n  \u003cdiv style=\"display: grid; gap: 10px; margin: 20px 0;\"\u003e\n\n    \u003cdiv style=\"border: 1px solid rgba(0,0,0,0.10); border-radius: 10px; padding: 12px;\"\u003e\n      \u003cstrong style=\"color: #154ba3;\"\u003eProduct Size:\u003c\/strong\u003e 10mg vial\n    \u003c\/div\u003e\n\n    \u003cdiv style=\"border: 1px solid rgba(0,0,0,0.10); border-radius: 10px; padding: 12px;\"\u003e\n      \u003cstrong style=\"color: #154ba3;\"\u003eCompound Class:\u003c\/strong\u003e Synthetic neuroendocrine decapeptide \/ KISS1R receptor agonist\n    \u003c\/div\u003e\n\n    \u003cdiv style=\"border: 1px solid rgba(0,0,0,0.10); border-radius: 10px; padding: 12px;\"\u003e\n      \u003cstrong style=\"color: #154ba3;\"\u003eSequence:\u003c\/strong\u003e Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH₂\n    \u003c\/div\u003e\n\n    \u003cdiv style=\"border: 1px solid rgba(0,0,0,0.10); border-radius: 10px; padding: 12px;\"\u003e\n      \u003cstrong style=\"color: #154ba3;\"\u003eMolecular Formula:\u003c\/strong\u003e C₆₃H₈₃N₁₇O₁₄\n    \u003c\/div\u003e\n\n    \u003cdiv style=\"border: 1px solid rgba(0,0,0,0.10); border-radius: 10px; padding: 12px;\"\u003e\n      \u003cstrong style=\"color: #154ba3;\"\u003eMolecular Weight:\u003c\/strong\u003e 1302.4 g\/mol\n    \u003c\/div\u003e\n\n    \u003cdiv style=\"border: 1px solid rgba(0,0,0,0.10); border-radius: 10px; padding: 12px;\"\u003e\n      \u003cstrong style=\"color: #154ba3;\"\u003eCAS Number:\u003c\/strong\u003e 374675-21-5\n    \u003c\/div\u003e\n\n    \u003cdiv style=\"border: 1px solid rgba(0,0,0,0.10); border-radius: 10px; padding: 12px;\"\u003e\n      \u003cstrong style=\"color: #154ba3;\"\u003eSynonyms:\u003c\/strong\u003e KP-10, Kisspeptin-10 Human, Human Metastin 45–54\n    \u003c\/div\u003e\n\n    \u003cdiv style=\"border: 1px solid rgba(0,0,0,0.10); border-radius: 10px; padding: 12px;\"\u003e\n      \u003cstrong style=\"color: #154ba3;\"\u003eComposition:\u003c\/strong\u003e Kisspeptin-10 lyophilized peptide\n    \u003c\/div\u003e\n\n    \u003cdiv style=\"border: 1px solid rgba(0,0,0,0.10); border-radius: 10px; padding: 12px;\"\u003e\n      \u003cstrong style=\"color: #154ba3;\"\u003eStorage:\u003c\/strong\u003e Store lyophilized material in a cool, dry, light-protected environment according to lot-specific instructions. Refrigeration is recommended after reconstitution. Minimize repeated freeze-thaw cycles.\n    \u003c\/div\u003e\n\n  \u003c\/div\u003e\n\n  \u003c!-- Why Researchers Study It --\u003e\n  \u003ch3 style=\"margin: 20px 0 8px; font-size: 19px; color: #154ba3;\"\u003e\n    Why Researchers Study Kisspeptin-10\n  \u003c\/h3\u003e\n\n  \u003cp style=\"margin: 8px 0 14px;\"\u003e\n    Kisspeptin-10 has gained substantial research interest because KISS1 and KISS1R signaling represents a major regulatory pathway connecting the hypothalamus with reproductive hormone signaling. The peptide provides a defined research model for examining receptor activation, GnRH-related communication, and downstream gonadotropin pathways.\n  \u003c\/p\u003e\n\n  \u003cp style=\"margin: 8px 0 18px;\"\u003e\n    Researchers also study Kisspeptin-10 in models involving reproductive development, puberty-related signaling, hormonal feedback, hypothalamic activity, and the broader relationship between metabolic and reproductive neuroendocrine systems.\n  \u003c\/p\u003e\n\n  \u003c!-- Disclaimer --\u003e\n  \u003cdiv style=\"background: #154ba3; color: #ffffff; border-radius: 12px; padding: 16px; margin-top: 22px;\"\u003e\n    \u003cstrong style=\"color: #ffffff;\"\u003eResearch Use Only:\u003c\/strong\u003e\n    \u003cp style=\"margin: 8px 0 0;\"\u003e\n      This product is intended strictly for laboratory and research purposes. Not for human consumption, medical use, diagnostic use, or therapeutic use.\n    \u003c\/p\u003e\n  \u003c\/div\u003e\n\n\u003c\/div\u003e","brand":"Method Peptides","offers":[{"title":"10mg","offer_id":49777032560778,"sku":null,"price":65.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0611\/5531\/1754\/files\/kisspeptin-10-10mg-method-peptides-vial.jpg?v=1784901482","url":"https:\/\/methodpeptides.com\/products\/kisspeptin-10","provider":"Method Peptides","version":"1.0","type":"link"}